Nebicor belongs to the group of the so-called beta blockers and is used for treatment of high blood pressure (hypertension).

Nebicor may also be used for treatment of stable mild to moderate chronic heart failure, in addition to the main treatment in patients aged 70 years or more. The heart failure is a heart disorder that most frequently leads to easy fatigue, breathlessness, ankle edema etc.

The dosage and duration of treatment are determined by your doctor depending on your condition.

Always take Nebicor exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

Treatment of high blood pressure (hypertension)

The usual dose is 5 mg (one 5 mg tablet or two 2,5 mg) daily, preferably at one and the same time of the day. The tablets may be taken during meals.

The antihypertensive (blood pressure lowering) effect is manifested within 1-2 weeks from the beginning of treatment. In some cases, 4 weeks are necessary for attaining optimal effect.

Patients with renal failure: In patients with renal failure the recommended initial dose is 2,5 mg (half a 5 mg tablet or one

2,5 mg) daily. If necessary, the daily dose may be increased to 5 mg.

Patients with liver failure: There are limited data in patients with liver failure or impaired liver function. Therefore, the use of the medicinal product in these patients is contraindicated.

Elderly patients: The recommended initial dose in patients over 65 years of age is 2,5 mg daily. If necessary, the daily dose may be increased to 5 mg. Nevertheless, due to the limited experience in patients over 75 years of age, this medicinal product should be used cautiously and under strict medical control.

Children and adolescents: No studies in children and adolescents were performed. Therefore, the use of the product in this group of patients is not recommended.

Chronic heart failure

Treatment in chronic heart failure should begin with gradual dose increase until the optimal maintenance dose for each patient is attained.

Dose titration (increase) should be done at 1-2-week interval depending on the individual tolerability of the patient as follows: the initial dose of 1,25 mg nebivolol should be increased to 2,5 mg nebivolol once daily, then to 5 mg once daily and finally to 10 mg once daily. The maximum recommended dose is 10 mg once daily.

Usually, treatment of stable heart failure with nebivolol is continuous.

If discontinuation of treatment is needed the dose should be gradually reduced (reduction by half, every week).

Children and adolescents: No studies in children and adolescents were performed. Therefore, the use of the product in this group of patients is not recommended.

Check with your doctor if you are not sure or have any further questions on your treatment with this medicinal product.