DRO SPAZ solution for injection lowers the smooth muscle tone of the viscera and the blood vessels by inhibiting (suppressing) the so-called enzyme phosphodiesterase. Upon intravenous administration, the onset of the spasmolytic effect is rapid.

Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. 

DRO SPAZ solution for injection is administered intramuscularly (in the muscles) or intravenously (in the veins). This medicinal product will be given to you by a health professional who will determine the dosage, route of administration and treatment duration. The usual daily dose in adults is 40 - 240 mg, divided in 1-3 intramuscular applications. In case of biliary or renal colics, the dose is 40-80 mg administered intravenously, alone or in combination with analgesics (painkillers). In case of uncomplicated labour in the phase of cervical dilation for decrease of the dilation duration and of the whole labour duration the dose is 40 mg intramuscularly. If necessary, this dose may be repeated every 2 hours (the maximum daily dose is 240 mg)

•     In spasms of the smooth muscles associated with disorders of the gall bladder and the biliary ways: stones in the gall bladder or the biliary ways, inflammation of the gall bladder or the biliary ways. 

•     In spasms of the smooth muscles in renal disorders and disorders of the bladder and the urinary tract: stones in the kidneys and the urinary tract, inflammation of the kidneys and the urinary tract, spasm of the bladder. 

•     In uncomplicated labour in the phase of cervical dilation for decrease of the dilation duration and the whole labour duration. 

When oral (through the mouth) intake is not possible, DRO SPAZ solution for injection may be also used in the following cases: 

•     Spasm of the smooth muscles of the gastrointestinal tract: gastric and duodenal ulcer, gastritis (inflammation of the stomach), spasm of the upper and the lower stomach muscles, bowel inflammation. 

•     In gynecological disorders: dysmenorrhea (painful periods) and relief of severe spastic pain during labour.