The active substance contained in this drug is the macrolide antibiotic azithromycin. It disrupts protein formation in the cells of different bacteria thus suppressing the growth and replication of the microorganisms causing common human diseases.

Adimax® is used for treatment of infections caused by bacteria susceptible to azithromycin, such as:

- upper respiratory tract infections: sore throat, tonsilitis, sinusitis, media ear infection

- lower respiratory tract infections: bronchitis, different types of pneumonia;

- skin and soft tissue infections: stage 1 of the Lyme disease (tick-transmitted disease), erysipelas, different bacterial skin infections;

Always take Adimax® exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Upper or lower respiratory tract infections, skin and soft tissue infections

Recommended dose is: 10 mg/kg once daily for 3 days. In case the sore throat is caused by a certain type of bacteria, the so called streptococci, your doctor may consider it necessary to administer a higher dose (20 mg/kg once daily).

To achieve appropriate dosing of the product according to body weight, please use the following information:

Body weight | Daily dose Adimax® 200 mg/5 ml, powder for oral suspension

10-14 kg                                 | 2.5 ml (100mg) 

15 – 24 kg (3 – 7 years)       | 5 ml (100mg) 

25 – 34 kg (8 – 11 years)      | 7.5 ml (300 mg)

35 – 44 kg (12 – 14 years)   | 10 ml (400 mg)

≥ 45 kg                                   | Dose as per adults 12.5 ml (500 mg)

In children up to 15 kg body weight (under 3 years of age): Determine the dose as accurately as possible using the oral dosing syringe provided with the pack.

Pneumonias

The recommended dose is 10 mg/kg once daily on the first day, and then 5 mg/kg once daily on days 2 to 5.

Lyme disease

Recommended dose: 20 mg/kg once daily on the first day and then 10 mg/kg once daily from day 2 to day 5. Total dose for the course of therapy: 60 mg/kg.

Kidney impairment

No dose adjustment is required in patients with mild renal function impairment. In case of severe renal impairment the doctor will assess if treatment with this product is possible, and the necessary dose adjustment.

Liver impairment

Since azithromycin is metabolized in the liver and excreted in the bile, the drug should not be used in patients with severe liver failure.

Method of administration

Adimax® powder for oral suspension should be used as a single daily dose. The precise dose should be measured after reconstitution of the suspension by using an oral dosing syringe provided with the pack.

The drug may be taken with or without food.

Instructions for reconstitution of the suspension

1. The bottle contains a dry powder which reconstitutes with water.

2. Turn the cap anticlockwise to open.

3. Fill the bottle with cold water. With oral dosing syringe provided with the pack you can measure the right amount of water. The right amount of water depends on the pack size:

- For pack size for 20 ml reconstituted suspension - add 10,5 ml of water

- For pack size for 30 ml reconstituted suspension - add 15 ml of water

4. Shake well until obtaining a homogeneous suspension.

5. Store reconstituted suspension below 30°C and discard when full dosing is completed.

6. Shake the suspension before each use.

Instructions for using the dosing syringe

1. Dip the tip of the dosing syringe in the suspension and use the plunger to withdraw the necessary amount .

2. Make sure the child is supported in a position for feeding, put the tip of the dosing syringe in the child’s mouth and slowly squirt the suspension.

3. Upon the intake of the medicinal product, give the child a small amount of juice or water.

4. After use, rinse the dosing device with water and store in a dry and clean place.